Injectable tesamorelin is a synthetic analog of growth hormone–releasing hormone (GHRH).
Helps in reduction of visceral adipose tissue (VAT) in HIV-infected patients with lipodystrophy, without significant loss of subcutaneous fat. It helps reduce hard-to-treat abdominal fat that is metabolically active and associated with cardiovascular risk.
Stimulates the pituitary gland to produce and release endogenous human growth hormone (GH), rather than providing GH directly.
This leads to a more physiological GH secretion pattern.
Possible improvement in lipid profiles (lower triglycerides).
Potential benefits on liver fat reduction (nonalcoholic fatty liver disease, or NAFLD).
Daily subcutaneous injection.
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